nanobiotix

NanoXray presentation

Cutting edge nanomedicine to transform cancer treatment

31^st October, 1:00 pm to 2:30 pm at Solamar Hotel, San Diego, USA

Don’t miss the unique opportunity to join the NanoXray presentation on October 31, 2010 to discover the most advanced technology for cancer treatment using nanoparticles.

It will provide a unique opportunity for attendees to get a deep understanding of cutting-edge nanomedecine, NanoXray platform technology and first clinical development.

Radiotherapy is known to be an effective treatment, however the impact of its physical effect is limited by the dose of radiation that healthy tissues can tolerate, resulting in a narrow therapeutic window and leaving a huge space for improvement. This space has marginally been filled by existing technologies, but none has been able to significantly improve the narrow therapeutic window of radiotherapy. The unmet medical need in this space is therefore tremendous, and nanoXray™ therapeutics may finally allow clinicians to use the full potential of the physical effect of radiation in oncology.

A new class of therapeutics based on nanoparticles called NanoXray™ therapeutics has been developed. This class consists of inert nanoparticles designed to enter tumor cells. Upon activation by a standard dose of radiation, they release a tremendous amount of energy that destroys cancer cells,  whilst the surrounding healthy tissues are preserved and receive the same dose of radiation as in standard  radiotherapy.

By significantly enhancing the power of radiotherapy, they could change the clinical outcome of radiotherapy and may also enable radiotherapy to play a larger role as a curative treatment. The mode of action of NanoXray™ nanoparticles is physical and has no specific target molecule interaction. The particles are inert and are “switched on” upon exposure to a  standard  Xray  source.  In  their  activated  state,  they  generate  free  oxygen  radicals which is the mode of action of radiotherapy, but by an order of magnitude far greater than radiotherapy alone, causing non-specific cellular damage leading to apoptosis or necrosis.